Keratinocyte-induced costimulation of human T cells through CD6 - but not CD2 - activates mTOR and prevents oxidative stress

In psoriasis and other inflammatory skin diseases, keratinocytes (KCs) secrete chemokines that attract T cells, which, in turn, cause epidermal hyperplasia by secreting proinflammatory cytokines. To date, it remains unclear whether skin-homing T cells, particularly memory T cells, can also be activa...

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Detalles Bibliográficos
Autores principales: Orlik, Christian, Berschneider, Karina M., Jahraus, Beate, Niesler, Beate, Balta, Emre, Schäkel, Knut, Schröder-Braunstein, Jutta, Souto-Carneiro, Maria Margarida, Samstag, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639098/
https://www.ncbi.nlm.nih.gov/pubmed/36353616
http://dx.doi.org/10.3389/fimmu.2022.1016112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639098/
https://www.ncbi.nlm.nih.gov/pubmed/36353616
http://dx.doi.org/10.3389/fimmu.2022.1016112

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