Polygenic risk score improves the accuracy of a clinical risk score for coronary artery disease

BACKGROUND: The value of polygenic risk scores (PRSs) towards improving guideline-recommended clinical risk models for coronary artery disease (CAD) prediction is controversial. Here we examine whether an integrated polygenic risk score improves the prediction of CAD beyond pooled cohort equations. ...

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Detalles Bibliográficos
Autores principales: King, Austin, Wu, Lang, Deng, Hong-Wen, Shen, Hui, Wu, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639312/
https://www.ncbi.nlm.nih.gov/pubmed/36336692
http://dx.doi.org/10.1186/s12916-022-02583-y

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