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PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation

BACKGROUND: Phosphatase and tensin homolog (PTEN) is a tumor suppressor. Low PTEN expression has been observed in pancreatic neuroendocrine tumors (pNETs) and is associated with increased liver metastasis and poor survival. Vascular endothelial growth factor receptor 3 (VEGFR3) is a receptor tyrosin...

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Detalles Bibliográficos
Autores principales:	Chang, Tsung-Ming, Chu, Pei-Yi, Lin, Hui-You, Huang, Kuo-Wei, Hung, Wen-Chun, Shan, Yan-Shen, Chen, Li-Tzong, Tsai, Hui-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639322/ https://www.ncbi.nlm.nih.gov/pubmed/36336681 http://dx.doi.org/10.1186/s12929-022-00875-2

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