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Long-term environmental exposure of darkness induces hyperandrogenism in PCOS via melatonin receptor 1A and aromatase reduction

Polycystic ovary syndrome (PCOS) is a common and complex disorder impairing female fertility, yet its etiology remains elusive. It is reported that circadian rhythm disruption might play a crucial role in PCOS pathologic progression. Here, in this research, we investigated the effect of environmenta...

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Detalles Bibliográficos
Autores principales:	Chu, Weiwei, Li, Shang, Geng, Xueying, Wang, Dongshuang, Zhai, Junyu, Lu, Gang, Chan, Wai-Yee, Chen, Zi-Jiang, Du, Yanzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639332/ https://www.ncbi.nlm.nih.gov/pubmed/36353509 http://dx.doi.org/10.3389/fcell.2022.954186

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