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Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity
Although various dual-target tubulin inhibitors have been designed and synthesised, no dual tubulin-NEDDylation inhibitors as antiproliferative agents were reported so far. In this work, a series of trimethoxyphenyl analogues as potential dual tubulin-NEDDylation inhibitors were synthesised and eval...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639481/ https://www.ncbi.nlm.nih.gov/pubmed/36330714 http://dx.doi.org/10.1080/14756366.2022.2136173 |