Single-cell transcriptomics of human gut T cells identifies cytotoxic CD4(+)CD8A(+) T cells related to mouse CD4 cytotoxic T cells

Cytotoxic CD4(+) T cells (CD4-CTLs) show the presence of cytolytic granules, which include the enzymes granzyme and perforin. The cells have a pathogenic and protective role in various diseases, including cancer, viral infection, and autoimmune disease. In mice, cytotoxic CD4(+) T cells express CD8α...

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Detalles Bibliográficos
Autores principales: Tanemoto, Shun, Sujino, Tomohisa, Miyamoto, Kentaro, Moody, Jonathan, Yoshimatsu, Yusuke, Ando, Yoshinari, Koya, Ikuko, Harada, Yosuke, Tojo, Anna Okuzawa, Ono, Keiko, Hayashi, Yukie, Takabayashi, Kaoru, Okabayashi, Koji, Teratani, Toshiaki, Mikami, Yohei, Nakamoto, Nobuhiro, Hosoe, Naoki, Ogata, Haruhiko, Hon, Chung-Chau, Shin, Jay W., Kanai, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639511/
https://www.ncbi.nlm.nih.gov/pubmed/36353619
http://dx.doi.org/10.3389/fimmu.2022.977117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639511/
https://www.ncbi.nlm.nih.gov/pubmed/36353619
http://dx.doi.org/10.3389/fimmu.2022.977117

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