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A New Crosslinking Assay to Study Guanine Nucleotide Binding in the Gtr Heterodimer of S. cerevisiae

The mechanistic target of rapamycin (mTOR) complex is responsible for coordinating nutrient availability with eukaryotic cell growth. Amino acid signals are transmitted towards mTOR via the Rag/Gtr heterodimers. Due to the obligatory heterodimeric architecture of the Rag/Gtr GTPases, investigating t...

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Detalles Bibliográficos
Autores principales: Doxsey, Dylan D., Veinotte, Kristen, Shen, Kuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639563/
https://www.ncbi.nlm.nih.gov/pubmed/36328771
http://dx.doi.org/10.1080/21541248.2022.2141019