Chitotriosidase is a biomarker for adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia

Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) leads to rapidly progressive dementia and is caused by mutations in the gene CSF1R. Neurodegeneration is driven by dysfunction of microglia, the predominant cell type expressing CSF1R in the brain. We assessed chitotrios...

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Detalles Bibliográficos
Autores principales: Hayer, Stefanie N., Santhanakumaran, Vidiyaah, Böhringer, Judith, Schöls, Ludger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639634/
https://www.ncbi.nlm.nih.gov/pubmed/36271674
http://dx.doi.org/10.1002/acn3.51656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639634/
https://www.ncbi.nlm.nih.gov/pubmed/36271674
http://dx.doi.org/10.1002/acn3.51656

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