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Mlh1 interacts with both Msh2 and Msh6 for recruitment during mismatch repair

Eukaryotic DNA mismatch repair (MMR) initiates through mispair recognition by the MutS homologs Msh2-Msh6 and Msh2-Msh3 and subsequent recruitment of the MutL homologs Mlh1-Pms1 (human MLH1-PMS2). In bacteria, MutL is recruited by interactions with the connector domain of one MutS subunit and the AT...

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Detalles Bibliográficos
Autores principales:	DuPrie, Matthew L., Palacio, Tatiana, Calil, Felipe A., Kolodner, Richard D., Putnam, Christopher D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639671/ https://www.ncbi.nlm.nih.gov/pubmed/36122480 http://dx.doi.org/10.1016/j.dnarep.2022.103405

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