Neurodegeneration Markers Galectin-3 and Apolipoprotein E Are Elevated in the Aqueous Humor of Eyes With Glaucoma

PURPOSE: Galectin-3 (Gal-3) and apolipoprotein E (APOE) are markers of activated microglia in neurodegenerative diseases of the central nervous system, whose targeting is protective in mouse models of glaucoma. In this study, we examined levels of Gal-3 and APOE in human aqueous humor (AH) and defin...

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Detalles Bibliográficos
Autores principales: Pitts, Kristen M., Neeson, Cameron E., Hall, Nathan E., Lin, Jonathan B., Falah, Henisk K., Wang, Silas L., Lo, Kristine T., Song, Christian E., Margeta, Milica A., Solá-Del Valle, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639679/
https://www.ncbi.nlm.nih.gov/pubmed/36318198
http://dx.doi.org/10.1167/tvst.11.11.1

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