Na(V)1.1 is essential for proprioceptive signaling and motor behaviors

The voltage-gated sodium channel (Na(V)), Na(V)1.1, is well-studied in the central nervous system; conversely, its contribution to peripheral sensory neuron function is more enigmatic. Here, we identify a new role for Na(V)1.1 in mammalian proprioception. RNAscope analysis and in vitro patch-clamp r...

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Detalles Bibliográficos
Autores principales: Espino, Cyrrus M, Lewis, Cheyanne M, Ortiz, Serena, Dalal, Miloni S, Garlapalli, Snigdha, Wells, Kaylee M, O'Neil, Darik A, Wilkinson, Katherine A, Griffith, Theanne N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640190/
https://www.ncbi.nlm.nih.gov/pubmed/36278870
http://dx.doi.org/10.7554/eLife.79917

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