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Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain

Protein tyrosine phosphatase receptor-type kappa (PTPRK) is a transmembrane receptor that links extracellular homophilic interactions to intracellular catalytic activity. Previously we showed that PTPRK promotes cell–cell adhesion by selectively dephosphorylating several cell junction regulators inc...

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Detalles Bibliográficos
Autores principales: Hay, Iain M, Mulholland, Katie E, Lai, Tiffany, Graham, Stephen C, Sharpe, Hayley J, Deane, Janet E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640194/
https://www.ncbi.nlm.nih.gov/pubmed/36264065
http://dx.doi.org/10.7554/eLife.79855