Interrogating the gating motions of the NaK channel

Previous crystallographic studies depicted a physical gate of the NaK channel localized at a bundle crossing of pore-lining helices, but solution NMR studies in the current issue of JGP suggest otherwise.

Detalles Bibliográficos
Autor principal: Rothberg, Brad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640267/
https://www.ncbi.nlm.nih.gov/pubmed/36326621
http://dx.doi.org/10.1085/jgp.202213257
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author Rothberg, Brad S.
author_facet Rothberg, Brad S.
author_sort Rothberg, Brad S.
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description Previous crystallographic studies depicted a physical gate of the NaK channel localized at a bundle crossing of pore-lining helices, but solution NMR studies in the current issue of JGP suggest otherwise.
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spelling pubmed-96402672023-05-03 Interrogating the gating motions of the NaK channel Rothberg, Brad S. J Gen Physiol Commentary Previous crystallographic studies depicted a physical gate of the NaK channel localized at a bundle crossing of pore-lining helices, but solution NMR studies in the current issue of JGP suggest otherwise. Rockefeller University Press 2022-11-03 /pmc/articles/PMC9640267/ /pubmed/36326621 http://dx.doi.org/10.1085/jgp.202213257 Text en © 2022 Rothberg https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Rothberg, Brad S.
Interrogating the gating motions of the NaK channel
title Interrogating the gating motions of the NaK channel
title_full Interrogating the gating motions of the NaK channel
title_fullStr Interrogating the gating motions of the NaK channel
title_full_unstemmed Interrogating the gating motions of the NaK channel
title_short Interrogating the gating motions of the NaK channel
title_sort interrogating the gating motions of the nak channel
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640267/
https://www.ncbi.nlm.nih.gov/pubmed/36326621
http://dx.doi.org/10.1085/jgp.202213257
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