Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the IGF1R-PI3K-AKT survival pathway

BACKGROUND: Hypertension is a severe public health risk factor worldwide. Elevated angiotensin II (Ang II) produced by the renin–angiotensin–aldosterone system can lead to hypertension and its complications. METHOD: In this study, we addressed the cardiac-injury effects of Ang II and investigated th...

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Detalles Bibliográficos
Autores principales: Lu, Shang-Yeh, Hong, Wei-Zhi, Tsai, Bruce Chi-Kang, Chang, Yu-Chun, Kuo, Chia-Hua, Mhone, Thomas G., Chen, Ray-Jade, Kuo, Wei-Wen, Huang, Chih-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640294/
https://www.ncbi.nlm.nih.gov/pubmed/36093879
http://dx.doi.org/10.1097/HJH.0000000000003285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640294/
https://www.ncbi.nlm.nih.gov/pubmed/36093879
http://dx.doi.org/10.1097/HJH.0000000000003285

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