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Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the IGF1R-PI3K-AKT survival pathway
BACKGROUND: Hypertension is a severe public health risk factor worldwide. Elevated angiotensin II (Ang II) produced by the renin–angiotensin–aldosterone system can lead to hypertension and its complications. METHOD: In this study, we addressed the cardiac-injury effects of Ang II and investigated th...
Autores principales: | Lu, Shang-Yeh, Hong, Wei-Zhi, Tsai, Bruce Chi-Kang, Chang, Yu-Chun, Kuo, Chia-Hua, Mhone, Thomas G., Chen, Ray-Jade, Kuo, Wei-Wen, Huang, Chih-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640294/ https://www.ncbi.nlm.nih.gov/pubmed/36093879 http://dx.doi.org/10.1097/HJH.0000000000003285 |
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