Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review

BACKGROUND: Malignant tumours of the aortic valve apparatus are extremely rare and difficult to diagnose. Their proximity to the coronary ostium may cause an acute coronary syndrome (ACS) either by infiltration or by embolization. CASE SUMMARY: We report a case of primary aortic valve undifferentiat...

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Autores principales: Parent, Martine, Lachapelle, Kevin, Issa-Chergui, Badia, Alcindor, Thierry, Genest, Jacques, Mousavi, Negareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Grand Round
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640299/
https://www.ncbi.nlm.nih.gov/pubmed/36381172
http://dx.doi.org/10.1093/ehjcr/ytac412
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author Parent, Martine
Lachapelle, Kevin
Issa-Chergui, Badia
Alcindor, Thierry
Genest, Jacques
Mousavi, Negareh
author_facet Parent, Martine
Lachapelle, Kevin
Issa-Chergui, Badia
Alcindor, Thierry
Genest, Jacques
Mousavi, Negareh
author_sort Parent, Martine
collection PubMed
description BACKGROUND: Malignant tumours of the aortic valve apparatus are extremely rare and difficult to diagnose. Their proximity to the coronary ostium may cause an acute coronary syndrome (ACS) either by infiltration or by embolization. CASE SUMMARY: We report a case of primary aortic valve undifferentiated sarcoma causing recurrent episodes of ACS, and we provide a literature review for primary cardiac valve tumours. This case also highlights the need for further evaluation of other causes of ACS in patients with minimal coronary artery disease risk factors and recurrent ACS. CONCLUSIONS: The majority of valve tumours are fibroelastomas. Sarcomas are rare and lead to poor outcomes.
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spelling pubmed-96402992022-11-14 Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review Parent, Martine Lachapelle, Kevin Issa-Chergui, Badia Alcindor, Thierry Genest, Jacques Mousavi, Negareh Eur Heart J Case Rep Grand Round BACKGROUND: Malignant tumours of the aortic valve apparatus are extremely rare and difficult to diagnose. Their proximity to the coronary ostium may cause an acute coronary syndrome (ACS) either by infiltration or by embolization. CASE SUMMARY: We report a case of primary aortic valve undifferentiated sarcoma causing recurrent episodes of ACS, and we provide a literature review for primary cardiac valve tumours. This case also highlights the need for further evaluation of other causes of ACS in patients with minimal coronary artery disease risk factors and recurrent ACS. CONCLUSIONS: The majority of valve tumours are fibroelastomas. Sarcomas are rare and lead to poor outcomes. Oxford University Press 2022-10-14 /pmc/articles/PMC9640299/ /pubmed/36381172 http://dx.doi.org/10.1093/ehjcr/ytac412 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Grand Round
Parent, Martine
Lachapelle, Kevin
Issa-Chergui, Badia
Alcindor, Thierry
Genest, Jacques
Mousavi, Negareh
Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review
title Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review
title_full Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review
title_fullStr Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review
title_full_unstemmed Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review
title_short Recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review
title_sort recurrent acute coronary syndrome caused by a primary aortic valve sarcoma: grand rounds and literature review
topic Grand Round
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640299/
https://www.ncbi.nlm.nih.gov/pubmed/36381172
http://dx.doi.org/10.1093/ehjcr/ytac412
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