Cargando…

BRD4 regulates the induction and maintenance of cancer stem cells in squamous cell carcinoma

Detalles Bibliográficos
Autores principales:	Hamad, Mawieh, Ali, Amjad, Muhammad, Jibran Sualeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Editorial Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640355/ https://www.ncbi.nlm.nih.gov/pubmed/36393920 http://dx.doi.org/10.21037/sci-2022-033

Ejemplares similares

Co-targeting BET bromodomain BRD4 and RAC1 suppresses growth, stemness and tumorigenesis by disrupting the c-MYC-G9a-FTH1axis and downregulating HDAC1 in molecular subtypes of breast cancer
por: Ali, Amjad, et al.
Publicado: (2021)

Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c‐MYC
por: Ali, Amjad, et al.
Publicado: (2021)

Vitamin D-Mediated Anti-cancer Activity Involves Iron Homeostatic Balance Disruption and Oxidative Stress Induction in Breast Cancer
por: Bajbouj, Khuloud, et al.
Publicado: (2021)

Genetic Mutations and Non-Coding RNA-Based Epigenetic Alterations Mediating the Warburg Effect in Colorectal Carcinogenesis
por: Abi Zamer, Batoul, et al.
Publicado: (2021)

SARS-CoV-2 Infection-Induced Promoter Hypomethylation as an Epigenetic Modulator of Heat Shock Protein A1L (HSPA1L) Gene
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2021)

Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2020)

SARS-CoV-2-induced hypomethylation of the ferritin heavy chain (FTH1) gene underlies serum hyperferritinemia in severe COVID-19 patients
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2022)

Plasma metabolomics profiling identifies new predictive biomarkers for disease severity in COVID-19 patients
por: Soares, Nelson C., et al.
Publicado: (2023)

Vitamin D Exerts Significant Antitumor Effects by Suppressing Vasculogenic Mimicry in Breast Cancer Cells
por: Bajbouj, Khuloud, et al.
Publicado: (2022)

Induction therapy in recurrent head and neck squamous cell carcinoma: is it time to consider response as a determinant of treatment selection?
por: Tasoulas, Jason, et al.
Publicado: (2023)

Therapeutic Targeting of BRD4 in Head Neck Squamous Cell Carcinoma
por: Wu, Yaping, et al.
Publicado: (2019)

KEYNOTE-407: new hope for the treatment of lung squamous cell carcinoma
por: Zhao, Xinmin, et al.
Publicado: (2020)

Diversity of the Origin of Cancer Stem Cells in Oral Squamous Cell Carcinoma and Its Clinical Implications
por: Fukumoto, Chonji, et al.
Publicado: (2022)

MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma
por: Manzoor, Shaista, et al.
Publicado: (2021)

New first-line treatment strategies for advanced lung squamous cell carcinoma
por: Cai, Xiuyu, et al.
Publicado: (2020)

Clinical patterns of seronegative spondyloarthropathies in a tertiary centre in Pakistan
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2018)

The prospect of combination therapy with immune checkpoint inhibitors and chemotherapy for squamous cell carcinoma of the lung
por: Ichiki, Yoshinobu, et al.
Publicado: (2020)

Utility of miRNA biomarkers for detection of early head and neck squamous cell carcinoma
por: Ershadifar, Soroush, et al.
Publicado: (2023)

Single nucleotide polymorphisms in microRNA binding sites on the HOX genes regulate carcinogenesis: An in-silico approach
por: El-Huneidi, Waseem, et al.
Publicado: (2021)

Eph receptor B2 (EPHB2) regulates cancer stem cell-like properties in hepatocellular carcinoma
por: Lim, Jhin Jieh, et al.
Publicado: (2022)

Sequential therapy with induction chemotherapy and chemoradiotherapy in pre-irradiated recurrent head and neck squamous cell carcinoma incorporating nab-paclitaxel—a commentary of the phase I trial of AFHX followed by concomitant FHX scheme
por: Martinez-Trufero, Javier, et al.
Publicado: (2023)

Revisiting checkpoint inhibitors for myeloma: maintenance after stem cell transplant
por: Meermeier, Erin W., et al.
Publicado: (2023)

Evolving treatment paradigms in recurrent and metastatic head and neck squamous cell carcinoma: the emergence of immunotherapy
por: Faraji, Farhoud, et al.
Publicado: (2023)

BRD4 promotes metastatic potential in oral squamous cell carcinoma through the epigenetic regulation of the MMP2 gene
por: Yamamoto, Tatsuro, et al.
Publicado: (2020)

JOSD1 promotes proliferation and chemoresistance of head and neck squamous cell carcinoma under the epigenetic regulation of BRD4
por: Jing, Chao, et al.
Publicado: (2021)

A new chapter in immune checkpoint inhibitor therapy: starting with advanced lung squamous cell carcinoma
por: Fei, Kailun, et al.
Publicado: (2020)

Regulation of Stemness in Carcinoma Cells
por: Hao, Jijun, et al.
Publicado: (2017)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell
por: Deeney, Jude T., et al.
Publicado: (2016)

Altered cell cycle regulation helps stem-like carcinoma cells resist apoptosis
por: Chappell, James, et al.
Publicado: (2010)

Adult Stem Cells in Tissue Maintenance and Regeneration
por: Montagnani, Stefania, et al.
Publicado: (2016)

Ins and Outs of Heat Shock Proteins in Colorectal Carcinoma: Its Role in Carcinogenesis and Therapeutic Perspectives
por: Abi Zamer, Batoul, et al.
Publicado: (2021)

Regulation of programmed cell death by Brd4
por: Hu, Jinfeng, et al.
Publicado: (2022)

Cell-surface GPNMB and induction of stemness
por: Okita, Yukari, et al.
Publicado: (2018)

Pancreatic Alpha Cells Hold the Key to Survival
por: Wali, Jibran A., et al.
Publicado: (2015)

Helicobacter pylori-induced DNA Methylation as an Epigenetic Modulator of Gastric Cancer: Recent Outcomes and Future Direction
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2019)

SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2022)

Improved diagnostic accuracy of hybrid positron emission tomography (PET) with tumor-specific radiotracer for head and neck squamous cell carcinoma staging
por: Morand, Grégoire B., et al.
Publicado: (2023)

Cancer stem cells in hepatocellular carcinomas
por: Das, Prasenjit, et al.
Publicado: (2015)

Outcomes of single versus two stage oesophagectomy for squamous cell carcinoma
por: Burton, Paul R
Publicado: (2020)

Commentary: Squamous cell carcinoma of the esophagus: Another target for checkpoint inhibition
por: Whyte, Richard I.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kh8bctj8qcpufavlhsq0jmgki1