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Homologous and heterologous booster vaccinations of S-268019-b, a recombinant S protein-based vaccine with a squalene-based adjuvant, enhance neutralization breadth against SARS-CoV-2 Omicron subvariants in cynomolgus macaques

SARS-CoV-2 Omicron subvariants such as BA.2.12.1, BA.4 and BA.5 have been spreading rapidly and become dominant worldwide. Here we report the homologous or heterologous booster effects of S-268019-b, a recombinant spike protein vaccine with the squalene-based adjuvant A-910823 in cynomolgus macaques...

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Detalles Bibliográficos
Autores principales:	Hashimoto, Masayuki, Aoe, Shinpei, Kawazu, Yusuke, Seki, Naomi M., Hashimoto, Kumi, Yoshihara, Ken, Homma, Tomoyuki, Sonoyama, Takuhiro, Omoto, Shinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier Ltd. 2022
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640394/ https://www.ncbi.nlm.nih.gov/pubmed/36372670 http://dx.doi.org/10.1016/j.vaccine.2022.10.092

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