SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail

Osteosarcomas (OS) are highly metastatic and usually lead to poor outcomes. Epithelial-mesenchymal transition (EMT) is reported to be a critical event in metastasis. SIRT2 exerts dual functions in many different tumors. However, the underlying molecular mechanisms of SIRT2 in osteosarcoma cell metas...

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Detalles Bibliográficos
Autores principales: Tian, Yonghao, Liu, Ruijuan, Hou, Xiaoyan, Gao, Zhixiao, Liu, Xinyu, Zhang, Weifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640536/
https://www.ncbi.nlm.nih.gov/pubmed/36344502
http://dx.doi.org/10.1038/s41419-022-05388-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640536/
https://www.ncbi.nlm.nih.gov/pubmed/36344502
http://dx.doi.org/10.1038/s41419-022-05388-2

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