Cargando…

Biochemical and genomic identification of novel biomarkers in progressive sarcoidosis: HBEGF, eNAMPT, and ANG-2

BACKGROUND: Progressive pulmonary fibrosis is a serious complication in subjects with sarcoidosis. The absence of reliable, non-invasive biomarkers that detect early progression exacerbates the difficulty in predicting sarcoidosis severity. To potentially address this unmet need, we evaluated a pane...

Descripción completa

Detalles Bibliográficos
Autores principales:	Casanova, Nancy G., Reyes-Hernon, Vivian, Gregory, Taylor, Sun, Belinda, Bermudez, Tadeo, Hufford, Matthew K., Oita, Radu C., Camp, Sara M., Hernandez-Molina, Gabriela, Serrano, Jorge Rojas, Sun, Xiaoguang, Fimbres, Jocelyn, Mirsaeidi, Mehdi, Sammani, Saad, Bime, Christian, Garcia, Joe G. N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640603/ https://www.ncbi.nlm.nih.gov/pubmed/36388923 http://dx.doi.org/10.3389/fmed.2022.1012827

Ejemplares similares

Linkage of NAMPT promoter variants to eNAMPT secretion, plasma eNAMPT levels, and ARDS severity
por: Lynn, Heather, et al.
Publicado: (2023)

Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody
por: Quijada, Hector, et al.
Publicado: (2021)

Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb
por: Ahmed, Mohamed, et al.
Publicado: (2021)

eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury
por: Sammani, Saad, et al.
Publicado: (2022)

Role of secreted extracellular nicotinamide phosphoribosyltransferase (eNAMPT) in prostate cancer progression: Novel biomarker and therapeutic target
por: Sun, Belinda L, et al.
Publicado: (2020)

eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling
por: Bermudez, Tadeo, et al.
Publicado: (2022)

Circulating eNAMPT as a biomarker in the critically ill: acute pancreatitis, sepsis, trauma, and acute respiratory distress syndrome
por: Bime, Christian, et al.
Publicado: (2022)

The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes
por: Ahmed, Mohamed, et al.
Publicado: (2023)

eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE Lung vasculitis and alveolar hemorrhage
por: Tumurkhuu, Gantsetseg, et al.
Publicado: (2022)

Is eNAMPT/visfatin a potential serum marker of papillary thyroid cancer?
por: Sawicka-Gutaj, Nadia, et al.
Publicado: (2022)

Circulating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure
por: Park, Jae Woo, et al.
Publicado: (2023)

Targeting SELPLG/P‐selectin glycoprotein ligand 1 in preclinical ARDS: Genetic and epigenetic regulation of the SELPLG promoter
por: Sun, Xiaoguang, et al.
Publicado: (2023)

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer
por: Travelli, Cristina, et al.
Publicado: (2023)

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma
por: Audrito, Valentina, et al.
Publicado: (2018)

eNAMPT Is Localised to Areas of Cartilage Damage in Patients with Hip Osteoarthritis and Promotes Cartilage Catabolism and Inflammation
por: Philp, Ashleigh M., et al.
Publicado: (2021)

eNAMPT actions through nucleus accumbens NAD(+)/SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress
por: Morató, Laia, et al.
Publicado: (2022)

Monomeric eNAMPT in the development of experimental diabetes in mice: a potential target for type 2 diabetes treatment
por: Kieswich, Julius, et al.
Publicado: (2016)

Colon-Targeted eNAMPT-Specific Peptide Systems for Treatment of DSS-Induced Acute and Chronic Colitis in Mouse
por: Kim, Jae-Sung, et al.
Publicado: (2022)

Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas
por: Casanova, Nancy G., et al.
Publicado: (2020)

Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress
por: Sun, Xiaoguang, et al.
Publicado: (2021)

Critical role for the lung endothelial nonmuscle myosin light‐chain kinase isoform in the severity of inflammatory murine lung injury
por: Kempf, Carrie L., et al.
Publicado: (2022)

Visfatin/eNampt induces endothelial dysfunction in vivo: a role for Toll-Like Receptor 4 and NLRP3 inflammasome
por: Romacho, Tania, et al.
Publicado: (2020)

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes
por: Sayers, Sophie R., et al.
Publicado: (2019)

The Cytokine Nicotinamide Phosphoribosyltransferase (eNAMPT; PBEF; Visfatin) Acts as a Natural Antagonist of C-C Chemokine Receptor Type 5 (CCR5)
por: Torretta, Simone, et al.
Publicado: (2020)

The acute respiratory distress syndrome biomarker pipeline: crippling gaps between discovery and clinical utility
por: Bime, Christian, et al.
Publicado: (2020)

NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway
por: Zhou, Lei, et al.
Publicado: (2020)

Regulation of HBEGF by Micro-RNA for Survival of Developing Human Trophoblast Cells
por: Jain, Chandni V., et al.
Publicado: (2016)

HBEGF promotes gliomagenesis in the context of Ink4a/Arf and Pten loss
por: Shin, Clifford H., et al.
Publicado: (2017)

Particulate matter promotes cancer metastasis through increased HBEGF expression in macrophages
por: Park, Seung-Ho, et al.
Publicado: (2022)

MiR-760 targets HBEGF to control cartilage extracellular matrix degradation in osteoarthritis
por: Zhu, Yingchun, et al.
Publicado: (2023)

Editorial: Sarcoidosis—The great mimicker
por: Korsten, Peter, et al.
Publicado: (2022)

Sarcoidosis-associated pulmonary fibrosis: joining the dots
por: Bandyopadhyay, Debabrata, et al.
Publicado: (2023)

Sarcoidosis or cancer? That is the question
por: Haddadi, Sara, et al.
Publicado: (2021)

Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo
por: Zhou, Zhen Ni, et al.
Publicado: (2013)

SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF
por: Xiao, Weikai, et al.
Publicado: (2020)

NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice
por: Sasaki, Keita, et al.
Publicado: (2015)

Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF
por: Lee, Sang In, et al.
Publicado: (2020)

HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids
por: Völkner, Manuela, et al.
Publicado: (2022)

Michel-Ange
por: Huyghe, René

Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury
por: Camp, Sara M., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mpf3rdk4odmciatn3l7pbtp7n7