Skeleton keys in the phage world

The viruses infecting bacteria, known as phages, carry a wondrous diversity of enzymes known as endolysins, which are responsible for opening cellular doors, like the membrane or wall, so that newly minted phages are set free. In a recent study, Oechslin and colleagues explored the evolutionary myst...

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Detalles Bibliográficos
Autor principal: Walker, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640615/
https://www.ncbi.nlm.nih.gov/pubmed/36344636
http://dx.doi.org/10.1038/s42003-022-04155-5
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author Walker, Melissa
author_facet Walker, Melissa
author_sort Walker, Melissa
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description The viruses infecting bacteria, known as phages, carry a wondrous diversity of enzymes known as endolysins, which are responsible for opening cellular doors, like the membrane or wall, so that newly minted phages are set free. In a recent study, Oechslin and colleagues explored the evolutionary mystery of lactococcal endolysin biodiversity, suggesting that these endolysins are flexible and can be used as kinds of skeleton keys to open a broad range of cellular doors.
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spelling pubmed-96406152022-11-15 Skeleton keys in the phage world Walker, Melissa Commun Biol Research Highlight The viruses infecting bacteria, known as phages, carry a wondrous diversity of enzymes known as endolysins, which are responsible for opening cellular doors, like the membrane or wall, so that newly minted phages are set free. In a recent study, Oechslin and colleagues explored the evolutionary mystery of lactococcal endolysin biodiversity, suggesting that these endolysins are flexible and can be used as kinds of skeleton keys to open a broad range of cellular doors. Nature Publishing Group UK 2022-11-07 /pmc/articles/PMC9640615/ /pubmed/36344636 http://dx.doi.org/10.1038/s42003-022-04155-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research Highlight
Walker, Melissa
Skeleton keys in the phage world
title Skeleton keys in the phage world
title_full Skeleton keys in the phage world
title_fullStr Skeleton keys in the phage world
title_full_unstemmed Skeleton keys in the phage world
title_short Skeleton keys in the phage world
title_sort skeleton keys in the phage world
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640615/
https://www.ncbi.nlm.nih.gov/pubmed/36344636
http://dx.doi.org/10.1038/s42003-022-04155-5
work_keys_str_mv AT walkermelissa skeletonkeysinthephageworld

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