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A formula to improve the reliability of optical axial length measurement in IOL power calculation
To verify the influence of axial length (AL) variations after cataract surgery in IOL power calculation. Patients underwent ophthalmic evaluation before surgery, including optical biometry with IOLMaster 500. Same exams were repeated 2 months after surgery: AL of operated eye was evaluated using two...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640640/ https://www.ncbi.nlm.nih.gov/pubmed/36344612 http://dx.doi.org/10.1038/s41598-022-23665-0 |
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author | De Bernardo, Maddalena Cione, Ferdinando Capasso, Luigi Coppola, Alessia Rosa, Nicola |
author_facet | De Bernardo, Maddalena Cione, Ferdinando Capasso, Luigi Coppola, Alessia Rosa, Nicola |
author_sort | De Bernardo, Maddalena |
collection | PubMed |
description | To verify the influence of axial length (AL) variations after cataract surgery in IOL power calculation. Patients underwent ophthalmic evaluation before surgery, including optical biometry with IOLMaster 500. Same exams were repeated 2 months after surgery: AL of operated eye was evaluated using two modes (pseudophakic/aphakic options). Mean Keratometry and AL changes were analyzed. Furthermore, refractive prediction error (PE) was back-calculated with Barrett Universal-II, Hoffer-Q, Holladay-1 and SRK/T formulas. To eliminate any systematic error, the mean error (ME) was zeroed-out for each formula. MEs and median absolute errors (MedAEs) of PEs were analyzed. Two-hundred-one operated eyes of 201 patients and 201 opposite eyes were evaluated. In operated eyes, mean AL difference was − 0.11 ± 0.07 mm (p < 0.001) with pseudophakic option and 0.00 ± 0.07 mm (p = 0.922) with aphakic option. There were not-statistically significant differences between MedAE of PEs calculated after zeroing-out the ME with different ALs (p > 0.05). Instead, only MEs of PEs obtained with postoperative ALs-pseudophakic option were not-statistically different from zero (p > 0.05). AL measurement change after cataract surgery is probably due to a systematic error in optical biometer in case of phakic eyes. A correction factor applied to preoperative AL could eliminate any systematic error in IOL power calculation without modifying the lens constant. |
format | Online Article Text |
id | pubmed-9640640 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-96406402022-11-15 A formula to improve the reliability of optical axial length measurement in IOL power calculation De Bernardo, Maddalena Cione, Ferdinando Capasso, Luigi Coppola, Alessia Rosa, Nicola Sci Rep Article To verify the influence of axial length (AL) variations after cataract surgery in IOL power calculation. Patients underwent ophthalmic evaluation before surgery, including optical biometry with IOLMaster 500. Same exams were repeated 2 months after surgery: AL of operated eye was evaluated using two modes (pseudophakic/aphakic options). Mean Keratometry and AL changes were analyzed. Furthermore, refractive prediction error (PE) was back-calculated with Barrett Universal-II, Hoffer-Q, Holladay-1 and SRK/T formulas. To eliminate any systematic error, the mean error (ME) was zeroed-out for each formula. MEs and median absolute errors (MedAEs) of PEs were analyzed. Two-hundred-one operated eyes of 201 patients and 201 opposite eyes were evaluated. In operated eyes, mean AL difference was − 0.11 ± 0.07 mm (p < 0.001) with pseudophakic option and 0.00 ± 0.07 mm (p = 0.922) with aphakic option. There were not-statistically significant differences between MedAE of PEs calculated after zeroing-out the ME with different ALs (p > 0.05). Instead, only MEs of PEs obtained with postoperative ALs-pseudophakic option were not-statistically different from zero (p > 0.05). AL measurement change after cataract surgery is probably due to a systematic error in optical biometer in case of phakic eyes. A correction factor applied to preoperative AL could eliminate any systematic error in IOL power calculation without modifying the lens constant. Nature Publishing Group UK 2022-11-07 /pmc/articles/PMC9640640/ /pubmed/36344612 http://dx.doi.org/10.1038/s41598-022-23665-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article De Bernardo, Maddalena Cione, Ferdinando Capasso, Luigi Coppola, Alessia Rosa, Nicola A formula to improve the reliability of optical axial length measurement in IOL power calculation |
title | A formula to improve the reliability of optical axial length measurement in IOL power calculation |
title_full | A formula to improve the reliability of optical axial length measurement in IOL power calculation |
title_fullStr | A formula to improve the reliability of optical axial length measurement in IOL power calculation |
title_full_unstemmed | A formula to improve the reliability of optical axial length measurement in IOL power calculation |
title_short | A formula to improve the reliability of optical axial length measurement in IOL power calculation |
title_sort | formula to improve the reliability of optical axial length measurement in iol power calculation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640640/ https://www.ncbi.nlm.nih.gov/pubmed/36344612 http://dx.doi.org/10.1038/s41598-022-23665-0 |
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