Discerning asthma endotypes through comorbidity mapping

Asthma is a heterogeneous, complex syndrome, and identifying asthma endotypes has been challenging. We hypothesize that distinct endotypes of asthma arise in disparate genetic variation and life-time environmental exposure backgrounds, and that disease comorbidity patterns serve as a surrogate for s...

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Detalles Bibliográficos
Autores principales: Jia, Gengjie, Zhong, Xue, Im, Hae Kyung, Schoettler, Nathan, Pividori, Milton, Hogarth, D. Kyle, Sperling, Anne I., White, Steven R., Naureckas, Edward T., Lyttle, Christopher S., Terao, Chikashi, Kamatani, Yoichiro, Akiyama, Masato, Matsuda, Koichi, Kubo, Michiaki, Cox, Nancy J., Ober, Carole, Rzhetsky, Andrey, Solway, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640644/
https://www.ncbi.nlm.nih.gov/pubmed/36344522
http://dx.doi.org/10.1038/s41467-022-33628-8

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