Structure of the IscB–ωRNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9

Transposon-encoded IscB family proteins are RNA-guided nucleases in the OMEGA (obligate mobile element-guided activity) system, and likely ancestors of the RNA-guided nuclease Cas9 in the type II CRISPR-Cas adaptive immune system. IscB associates with its cognate ωRNA to form a ribonucleoprotein com...

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Detalles Bibliográficos
Autores principales: Kato, Kazuki, Okazaki, Sae, Kannan, Soumya, Altae-Tran, Han, Esra Demircioglu, F., Isayama, Yukari, Ishikawa, Junichiro, Fukuda, Masahiro, Macrae, Rhiannon K., Nishizawa, Tomohiro, Makarova, Kira S., Koonin, Eugene V., Zhang, Feng, Nishimasu, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640706/
https://www.ncbi.nlm.nih.gov/pubmed/36344504
http://dx.doi.org/10.1038/s41467-022-34378-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640706/
https://www.ncbi.nlm.nih.gov/pubmed/36344504
http://dx.doi.org/10.1038/s41467-022-34378-3

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