Cargando…

Randomized, double-blind, placebo-controlled, crossover trial of oral doxycycline for epistaxis in hereditary hemorrhagic telangiectasia

BACKGROUND: Vascular malformations in hereditary hemorrhagic telangiectasia (HHT) lead to chronic recurrent bleeding, hemorrhage, stroke, heart failure, and liver disease. There is great interest in identifying novel therapies for epistaxis in HHT given its associated morbidity and impact on quality...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thompson, K. P., Sykes, J., Chandakkar, P., Marambaud, P., Vozoris, N. T., Marchuk, D. A., Faughnan, M. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640829/ https://www.ncbi.nlm.nih.gov/pubmed/36344987 http://dx.doi.org/10.1186/s13023-022-02539-8

Ejemplares similares

Weekly epistaxis duration as an indicator of epistaxis severity in hereditary hemorrhagic telangiectasia—Preliminary results from a randomized controlled trial
por: Wu, Vincent, et al.
Publicado: (2021)

Predictors of mortality in patients with hereditary hemorrhagic telangiectasia
por: Thompson, K. P., et al.
Publicado: (2021)

Prospective pilot study of Floseal® for the treatment of anterior epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT)
por: Lee, John M., et al.
Publicado: (2019)

Utility of modified Rankin Scale for brain vascular malformations in hereditary hemorrhagic telangiectasia
por: Thompson, K. P., et al.
Publicado: (2021)

Topical Propranolol Improves Epistaxis Control in Hereditary Hemorrhagic Telangiectasia (HHT): A Randomized Double-Blind Placebo-Controlled Trial
por: Mei-Zahav, Meir, et al.
Publicado: (2020)

Efficacy of TIMOLOL nasal spray as a treatment for epistaxis in hereditary hemorrhagic telangiectasia. A double-blind, randomized, placebo-controlled trial
por: Dupuis-Girod, Sophie, et al.
Publicado: (2019)

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia
por: Faughnan, Marie E., et al.
Publicado: (2018)

Very low dose bevacizumab for the treatment of epistaxis in patients with hereditary hemorrhagic telangiectasia
por: Thompson, Andrew B., et al.
Publicado: (2014)

Synthetic dural graft septoplasty in epistaxis from hereditary hemorrhagic telangiectasia
por: Burckhardt B, Wilfred, et al.
Publicado: (2013)

Epistaxis in hereditary hemorrhagic telangiectasia: an evidence based review of surgical management
por: Chin, Christopher J., et al.
Publicado: (2016)

A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10
por: Ruiz, Santiago, et al.
Publicado: (2016)

Severity score for hereditary hemorrhagic telangiectasia
por: Latino, Giuseppe A, et al.
Publicado: (2014)

Can Iron Treatments Aggravate Epistaxis in Some Patients With Hereditary Hemorrhagic Telangiectasia?
por: Shovlin, Claire L., et al.
Publicado: (2016)

CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia
por: Dinakaran, Sajeth, et al.
Publicado: (2023)

Topical propranolol improves epistaxis in patients with hereditary hemorrhagic telangiectasia - a preliminary report
por: Mei-Zahav, Meir, et al.
Publicado: (2017)

Hereditary hemorrhagic telangiectasia presenting as a recurrent epistaxis in an adolescent: A case report
por: Acharya, Ratna, et al.
Publicado: (2021)

Efficacy and Safety of a 0.1% Tacrolimus Nasal Ointment as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia: A Double-Blind, Randomized, Placebo-Controlled, Multicenter Trial
por: Dupuis-Girod, Sophie, et al.
Publicado: (2020)

Diode laser in the treatment of epistaxis in patients with hereditary haemorrhagic telangiectasia
por: FIORELLA, M.L., et al.
Publicado: (2012)

An analysis of sex differences in pulmonary arteriovenous malformation presentation, complications and management in a large, multinational registry of patients with hereditary haemorrhagic telangiectasia
por: Tuff-Gordon, Eliza, et al.
Publicado: (2023)

Circulating Angiogenic Cell Dysfunction in Patients with Hereditary Hemorrhagic Telangiectasia
por: Zucco, Liana, et al.
Publicado: (2014)

Endoscopic surgical treatment of epistaxis in hereditary haemorrhagic telangiectasia: our experience
por: Pagella, Fabio, et al.
Publicado: (2021)

Association of common candidate variants with vascular malformations and intracranial hemorrhage in hereditary hemorrhagic telangiectasia
por: Pawlikowska, Ludmila, et al.
Publicado: (2018)

Hereditary Hemorrhagic Telangiectasia
por: Kamath, Nagesh, et al.
Publicado: (2015)

TIMolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (TIM-HHT)—A Prospective, Randomized, Double-Blind, Controlled, Cross-Over Trial
por: Andorfer, Kornelia E. C., et al.
Publicado: (2022)

Thalidomide for the Management of Bleeding Episodes in Patients with Hereditary Hemorrhagic Telangiectasia: Effects on Epistaxis Severity Score and Quality of Life
por: Baysal, Mehmet, et al.
Publicado: (2019)

Integration of clinical parameters, genotype and epistaxis severity score to guide treatment for hereditary hemorrhagic telangiectasia associated bleeding
por: Beckman, Joan D., et al.
Publicado: (2020)

Targeting under-diagnosis in hereditary hemorrhagic telangiectasia: a model approach for rare diseases?
por: Latino, Giuseppe A, et al.
Publicado: (2014)

High-Output Heart Failure Contributing to Recurrent Epistaxis Kiesselbach Area Syndrome in a Patient With Hereditary Hemorrhagic Telangiectasia
por: Bhattad, Venugopal Brijmohan, et al.
Publicado: (2017)

Imaging of Hereditary Hemorrhagic Telangiectasia
por: Carette, Marie-France, et al.
Publicado: (2008)

Lactulose to the Rescue: A Case of Toxic Hepatic Encephalopathy Caused by Portosystemic Shunting and Epistaxis in a Patient with Hereditary Hemorrhagic Telangiectasia
por: Shah, Ruchit N., et al.
Publicado: (2019)

Life expextancy of parents with Hereditary Haemorrhagic Telangiectasia
por: de Gussem, E. M., et al.
Publicado: (2016)

Gender differences in hereditary hemorrhagic telangiectasia severity
por: Mora-Luján, J. M., et al.
Publicado: (2020)

Optimal management of hereditary hemorrhagic telangiectasia
por: Garg, Neetika, et al.
Publicado: (2014)

Hereditary Hemorrhagic Telangiectasia with Unusual Associations
por: Jain, Dheeraj, et al.
Publicado: (2015)

Pericytes as targets in hereditary hemorrhagic telangiectasia
por: Thalgott, Jérémy, et al.
Publicado: (2015)

Hypercoagulability in hereditary hemorrhagic telangiectasia with epilepsy
por: Finsterer, Josef, et al.
Publicado: (2015)

Splenic Involvement in Hereditary Hemorrhagic Telangiectasia
por: Takamatsu, Susumu, et al.
Publicado: (2016)

Hereditary hemorrhagic telangiectasia with hemothorax in pregnancy
por: Raiya, Sagar, et al.
Publicado: (2017)

Hereditary Hemorrhagic Telangiectasia and Refractory Ascites
por: Thandassery, Ragesh B., et al.
Publicado: (2020)

Future treatments for hereditary hemorrhagic telangiectasia
por: Robert, Florian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_553ntl3gslf343p1rf9v6e64ki