A randomized clinical trial of lipid metabolism modulation with fenofibrate for acute coronavirus disease 2019

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cytotoxicity may involve inhibition of peroxisome proliferator-activated receptor alpha. Fenofibrate activates peroxisome proliferator-activated receptor alpha and inhibits SARS-CoV-2 replication in vitro. Whether fenofibrate can be used t...

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Autores principales: Chirinos, Julio A., Lopez-Jaramillo, Patricio, Giamarellos-Bourboulis, Evangelos J., Dávila-del-Carpio, Gonzalo H., Bizri, Abdul Rahman, Andrade-Villanueva, Jaime F., Salman, Oday, Cure-Cure, Carlos, Rosado-Santander, Nelson R., Cornejo Giraldo, Mario P., González-Hernández, Luz A., Moghnieh, Rima, Angeliki, Rapti, Cruz Saldarriaga, María E., Pariona, Marcos, Medina, Carola, Dimitroulis, Ioannis, Vlachopoulos, Charalambos, Gutierrez, Corina, Rodriguez-Mori, Juan E., Gomez-Laiton, Edgar, Cotrina Pereyra, Rosa, Ravelo Hernández, Jorge Luis, Arbañil, Hugo, Accini-Mendoza, José, Pérez-Mayorga, Maritza, Milionis, Charalampos, Poulakou, Garyfallia, Sánchez, Gregorio, Valdivia-Vega, Renzo, Villavicencio-Carranza, Mirko, Ayala-García, Ricardo J., Castro-Callirgos, Carlos A., Alfaro Carrasco, Rosa M., Garrido Lecca Danos, Willy, Sharkoski, Tiffany, Greene, Katherine, Pourmussa, Bianca, Greczylo, Candy, Ortega-Legaspi, Juan, Jacoby, Douglas, Chittams, Jesse, Katsaounou, Paraskevi, Alexiou, Zoi, Sympardi, Styliani, Sweitzer, Nancy K., Putt, Mary, Cohen, Jordana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640855/
https://www.ncbi.nlm.nih.gov/pubmed/36344766
http://dx.doi.org/10.1038/s42255-022-00698-3

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