Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice

Hypertension is one of the common causes of pathological cardiac hypertrophy and a major risk for morbidity and mortality of cardiovascular diseases worldwide. Ubiquitin-Specific Protease 7 (USP7), the first identified deubiquitinating enzymes, participated in a variety of biological processes, such...

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Detalles Bibliográficos
Autores principales: Gu, Yu-Hui, Ren, Kai-Wen, Wang, Yu, Wang, Shi-Hao, Yu, Xiao-Hong, Xu, Li-Wen, Li, Hui-Hua, Bi, Hai-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640964/
https://www.ncbi.nlm.nih.gov/pubmed/36386139
http://dx.doi.org/10.3389/fphar.2022.1021361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640964/
https://www.ncbi.nlm.nih.gov/pubmed/36386139
http://dx.doi.org/10.3389/fphar.2022.1021361

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