Cargando…
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice
Hypertension is one of the common causes of pathological cardiac hypertrophy and a major risk for morbidity and mortality of cardiovascular diseases worldwide. Ubiquitin-Specific Protease 7 (USP7), the first identified deubiquitinating enzymes, participated in a variety of biological processes, such...
Autores principales: | Gu, Yu-Hui, Ren, Kai-Wen, Wang, Yu, Wang, Shi-Hao, Yu, Xiao-Hong, Xu, Li-Wen, Li, Hui-Hua, Bi, Hai-Lian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640964/ https://www.ncbi.nlm.nih.gov/pubmed/36386139 http://dx.doi.org/10.3389/fphar.2022.1021361 |
Ejemplares similares
-
Ang II Promotes Cardiac Autophagy and Hypertrophy via Orai1/STIM1
por: Zheng, Chang-Bo, et al.
Publicado: (2021) -
USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis
por: Fan, Y-H, et al.
Publicado: (2013) -
Cardiac-specific knockdown of Bhlhe40 attenuates angiotensin II (Ang II)-Induced atrial fibrillation in mice
por: Ren, Kai-Wen, et al.
Publicado: (2022) -
Selective Inhibition of the Immunoproteasome β5i Prevents PTEN Degradation and Attenuates Cardiac Hypertrophy
por: Xie, Xin, et al.
Publicado: (2020) -
P22077 inhibits LPS-induced inflammatory response by promoting K48-linked ubiquitination and degradation of TRAF6
por: Zhao, Xi-Bao, et al.
Publicado: (2020)