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Physiological levels of adrenaline fail to stop pancreatic beta cell activity at unphysiologically high glucose levels
Adrenaline inhibits insulin secretion from pancreatic beta cells to allow an organism to cover immediate energy needs by unlocking internal nutrient reserves. The stimulation of α2-adrenergic receptors on the plasma membrane of beta cells reduces their excitability and insulin secretion mostly throu...
Autores principales: | Sluga, Nastja, Križančić Bombek, Lidija, Kerčmar, Jasmina, Sarikas, Srdjan, Postić, Sandra, Pfabe, Johannes, Skelin Klemen, Maša, Korošak, Dean, Stožer, Andraž, Slak Rupnik, Marjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9640998/ https://www.ncbi.nlm.nih.gov/pubmed/36387857 http://dx.doi.org/10.3389/fendo.2022.1013697 |
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