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Plasma RNA profiling unveils transcriptional signatures associated with resistance to osimertinib in EGFR T790M positive non-small cell lung cancer patients
BACKGROUND: Targeted therapy with tyrosine kinases inhibitors (TKIs) against epidermal growth factor receptor (EGFR) is part of routine clinical practice for EGFR mutant advanced non-small cell lung cancer (NSCLC) patients. These patients eventually develop resistance, frequently accompanied by a ga...
Autores principales: | Alexeyenko, Andrey, Brustugun, Odd Terje, Eide, Inger Johanne Zwicky, Gencheva, Radosveta, Kosibaty, Zeinab, Lai, Yi, de Petris, Luigi, Tsakonas, Georgios, Grundberg, Oscar, Franzen, Bo, Viktorsson, Kristina, Lewensohn, Rolf, Hydbring, Per, Ekman, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641044/ https://www.ncbi.nlm.nih.gov/pubmed/36386450 http://dx.doi.org/10.21037/tlcr-22-236 |
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