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Prognostic stratification based on the levels of tumor-infiltrating myeloid-derived suppressor cells and PD-1/PD-L1 axis in locally advanced rectal cancer

BACKGROUND: Although rectal cancer remains somewhat sanctuary to the contemporary immunotherapy, there is increasing knowledge on clinical implications of anti-tumor immunity. This study evaluated the prognostic relevance of two immune-inhibitory functions, myeloid-derived suppressor cells (MDSCs) a...

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Detalles Bibliográficos
Autores principales: Lim, Yu Jin, Koh, Jaemoon, Choi, Minji, Kim, Sehui, Chie, Eui Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641101/
https://www.ncbi.nlm.nih.gov/pubmed/36387259
http://dx.doi.org/10.3389/fonc.2022.1018700