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Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging

BACKGROUND: To explore the diagnostic and therapeutic effects of multi-dimensional conformal radiotherapy (MD-CRT) combined with functional imaging in tumor bioimaging. METHODS: A total of 150 cases of patients with brain metastases in First Affiliated Hospital of Xi’an Jiaotong University between D...

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Detalles Bibliográficos
Autores principales: Huang, Dabei, He, Lan, Xiong, Minchao, Sun, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641124/
https://www.ncbi.nlm.nih.gov/pubmed/36388020
http://dx.doi.org/10.21037/tcr-22-2005
Descripción
Sumario:BACKGROUND: To explore the diagnostic and therapeutic effects of multi-dimensional conformal radiotherapy (MD-CRT) combined with functional imaging in tumor bioimaging. METHODS: A total of 150 cases of patients with brain metastases in First Affiliated Hospital of Xi’an Jiaotong University between December 2020 and December 2021 were retrospectively selected as the research cohort. Participants underwent whole brain imaging guided by MD-CRT combined with volume assessment to assess the patient’s recent treatment effect, statistically acceptable dose irradiation treatment, and the incidence of adverse reactions. All patients were followed up to evaluate the long-term efficacy. RESULTS: Among the 150 patients, 24 cases were in complete remission, 72 cases were in partial remission, 36 cases were in a stable condition, 18 cases were in deterioration, and the treatment of 96 cases (64.00%) was deemed effective. All participants were followed up, the mean survival was (62.37±1.24) months, 96 cases (64.00%) survived, and 54 cases (36.00%) had died. The average dose was (62.09±3.94) Gy. In terms of adverse reactions: brain edema occurred in 57 patients, accounting for 38.00%. CONCLUSIONS: The MD-CRT and functional imaging techniques for patients with metastatic tumor have high therapeutic accuracy, are associated with improved local control rate, prolonged survival, and cause little damage to normal tissues, with significant therapeutic effect, and can be widely used in clinical practice.