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Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging

BACKGROUND: To explore the diagnostic and therapeutic effects of multi-dimensional conformal radiotherapy (MD-CRT) combined with functional imaging in tumor bioimaging. METHODS: A total of 150 cases of patients with brain metastases in First Affiliated Hospital of Xi’an Jiaotong University between D...

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Autores principales: Huang, Dabei, He, Lan, Xiong, Minchao, Sun, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641124/
https://www.ncbi.nlm.nih.gov/pubmed/36388020
http://dx.doi.org/10.21037/tcr-22-2005
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author Huang, Dabei
He, Lan
Xiong, Minchao
Sun, Qing
author_facet Huang, Dabei
He, Lan
Xiong, Minchao
Sun, Qing
author_sort Huang, Dabei
collection PubMed
description BACKGROUND: To explore the diagnostic and therapeutic effects of multi-dimensional conformal radiotherapy (MD-CRT) combined with functional imaging in tumor bioimaging. METHODS: A total of 150 cases of patients with brain metastases in First Affiliated Hospital of Xi’an Jiaotong University between December 2020 and December 2021 were retrospectively selected as the research cohort. Participants underwent whole brain imaging guided by MD-CRT combined with volume assessment to assess the patient’s recent treatment effect, statistically acceptable dose irradiation treatment, and the incidence of adverse reactions. All patients were followed up to evaluate the long-term efficacy. RESULTS: Among the 150 patients, 24 cases were in complete remission, 72 cases were in partial remission, 36 cases were in a stable condition, 18 cases were in deterioration, and the treatment of 96 cases (64.00%) was deemed effective. All participants were followed up, the mean survival was (62.37±1.24) months, 96 cases (64.00%) survived, and 54 cases (36.00%) had died. The average dose was (62.09±3.94) Gy. In terms of adverse reactions: brain edema occurred in 57 patients, accounting for 38.00%. CONCLUSIONS: The MD-CRT and functional imaging techniques for patients with metastatic tumor have high therapeutic accuracy, are associated with improved local control rate, prolonged survival, and cause little damage to normal tissues, with significant therapeutic effect, and can be widely used in clinical practice.
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spelling pubmed-96411242022-11-15 Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging Huang, Dabei He, Lan Xiong, Minchao Sun, Qing Transl Cancer Res Original Article BACKGROUND: To explore the diagnostic and therapeutic effects of multi-dimensional conformal radiotherapy (MD-CRT) combined with functional imaging in tumor bioimaging. METHODS: A total of 150 cases of patients with brain metastases in First Affiliated Hospital of Xi’an Jiaotong University between December 2020 and December 2021 were retrospectively selected as the research cohort. Participants underwent whole brain imaging guided by MD-CRT combined with volume assessment to assess the patient’s recent treatment effect, statistically acceptable dose irradiation treatment, and the incidence of adverse reactions. All patients were followed up to evaluate the long-term efficacy. RESULTS: Among the 150 patients, 24 cases were in complete remission, 72 cases were in partial remission, 36 cases were in a stable condition, 18 cases were in deterioration, and the treatment of 96 cases (64.00%) was deemed effective. All participants were followed up, the mean survival was (62.37±1.24) months, 96 cases (64.00%) survived, and 54 cases (36.00%) had died. The average dose was (62.09±3.94) Gy. In terms of adverse reactions: brain edema occurred in 57 patients, accounting for 38.00%. CONCLUSIONS: The MD-CRT and functional imaging techniques for patients with metastatic tumor have high therapeutic accuracy, are associated with improved local control rate, prolonged survival, and cause little damage to normal tissues, with significant therapeutic effect, and can be widely used in clinical practice. AME Publishing Company 2022-10 /pmc/articles/PMC9641124/ /pubmed/36388020 http://dx.doi.org/10.21037/tcr-22-2005 Text en 2022 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Huang, Dabei
He, Lan
Xiong, Minchao
Sun, Qing
Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging
title Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging
title_full Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging
title_fullStr Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging
title_full_unstemmed Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging
title_short Study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging
title_sort study on the value of multi-dimensional conformal radiotherapy and functional imaging in tumor bioimaging
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641124/
https://www.ncbi.nlm.nih.gov/pubmed/36388020
http://dx.doi.org/10.21037/tcr-22-2005
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