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Assessment of potential drug–drug interactions among outpatients in a tertiary care hospital: focusing on the role of P-glycoprotein and CYP3A4 (retrospective observational study)

BACKGROUND: Selecting a medicine has a significant impact on the quality of therapy including efficacy and safety. P-glycoprotein and CYP3A4 share several common substrates known as bi-substrates. Both play major role in the pharmacokinetics and pharmacodynamics when over or under expressed. OBJECTI...

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Detalles Bibliográficos
Autores principales:	Patel, Krupa A., Bhatt, Masumi H., Hirani, Rajvi V., Patel, Vidheesha A., Patel, Vishvas N., Shah, Gaurang B., Chorawala, Mehul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641194/ https://www.ncbi.nlm.nih.gov/pubmed/36387483 http://dx.doi.org/10.1016/j.heliyon.2022.e11278

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