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Age-differential sexual dimorphism in CHD8-S62X-mutant mouse behaviors

Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~4:1), although the underlying mechanism remains unclear. Chd8-mutant mice with a C-terminal protein-truncating mutation (N2373K) display male-prepon...

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Detalles Bibliográficos
Autores principales:	Lee, Soo Yeon, Kweon, Hanseul, Kang, Hyojin, Kim, Eunjoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641250/ https://www.ncbi.nlm.nih.gov/pubmed/36385756 http://dx.doi.org/10.3389/fnmol.2022.1022306

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