Shikonin induces ferroptosis in multiple myeloma via GOT1-mediated ferritinophagy

Multiple myeloma (MM) is an incurable hematological malignancy that lacks effective therapeutic interventions. Ferroptosis is a newly discovered form of cell death that has shown great potential for MM therapy. As a proteasome inhibitor and necroptosis inducer, shikonin (SHK) performs dual functions...

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Detalles Bibliográficos
Autores principales: Li, Wenxia, Fu, Hangjie, Fang, Liuyuan, Chai, Hui, Gao, Tianwen, Chen, Zhenzhen, Qian, Shenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641271/
https://www.ncbi.nlm.nih.gov/pubmed/36387145
http://dx.doi.org/10.3389/fonc.2022.1025067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641271/
https://www.ncbi.nlm.nih.gov/pubmed/36387145
http://dx.doi.org/10.3389/fonc.2022.1025067

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