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The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period

Modern literature data indicate that the role of trypsin goes far beyond its digestive function. Once in the blood, trypsin is involved as part of the kallikrein-kinin system in the regulation of blood pressure, regulates pancreatic function by activating PAR receptors, and influences inflammation a...

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Autores principales: Vertiprakhov, Vladimir G., Ovchinnikova, Natalya V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641294/
https://www.ncbi.nlm.nih.gov/pubmed/36388123
http://dx.doi.org/10.3389/fphys.2022.874664
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author Vertiprakhov, Vladimir G.
Ovchinnikova, Natalya V.
author_facet Vertiprakhov, Vladimir G.
Ovchinnikova, Natalya V.
author_sort Vertiprakhov, Vladimir G.
collection PubMed
description Modern literature data indicate that the role of trypsin goes far beyond its digestive function. Once in the blood, trypsin is involved as part of the kallikrein-kinin system in the regulation of blood pressure, regulates pancreatic function by activating PAR receptors, and influences inflammation and immunity in the cell. The interaction of trypsin in the intestine and serum in the living healthy organism has been insufficiently studied. On the basis of our own studies and literature data, we concluded that after overnight fasting the increase of trypsin activity in pancreatic juice and blood serum in the postprandial period occurs in parallel, which determines not only digestion of food protein but also the level of metabolism. Consequently, determining the optimal amount of crude protein in the diet during the morning meal is a paramount task for physiologists.
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spelling pubmed-96412942022-11-15 The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period Vertiprakhov, Vladimir G. Ovchinnikova, Natalya V. Front Physiol Physiology Modern literature data indicate that the role of trypsin goes far beyond its digestive function. Once in the blood, trypsin is involved as part of the kallikrein-kinin system in the regulation of blood pressure, regulates pancreatic function by activating PAR receptors, and influences inflammation and immunity in the cell. The interaction of trypsin in the intestine and serum in the living healthy organism has been insufficiently studied. On the basis of our own studies and literature data, we concluded that after overnight fasting the increase of trypsin activity in pancreatic juice and blood serum in the postprandial period occurs in parallel, which determines not only digestion of food protein but also the level of metabolism. Consequently, determining the optimal amount of crude protein in the diet during the morning meal is a paramount task for physiologists. Frontiers Media S.A. 2022-10-25 /pmc/articles/PMC9641294/ /pubmed/36388123 http://dx.doi.org/10.3389/fphys.2022.874664 Text en Copyright © 2022 Vertiprakhov and Ovchinnikova. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Vertiprakhov, Vladimir G.
Ovchinnikova, Natalya V.
The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period
title The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period
title_full The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period
title_fullStr The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period
title_full_unstemmed The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period
title_short The activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period
title_sort activity of trypsin in the pancreatic juice and blood of poultry increases simultaneously in the postprandial period
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641294/
https://www.ncbi.nlm.nih.gov/pubmed/36388123
http://dx.doi.org/10.3389/fphys.2022.874664
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