Metformin-induced AMPK activation promotes cisplatin resistance through PINK1/Parkin dependent mitophagy in gastric cancer

Gastric cancer (GC) is one of the most common tumors worldwide, and cisplatin is a standard chemotherapeutic reagent for GC treatment. However, chemoresistance is an inherent challenge which limits its application and effectiveness in clinic. This study aims to investigate the mechanism of metformin...

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Detalles Bibliográficos
Autores principales: Xiao, Yi-Yi, Xiao, Jin-Xing, Wang, Xiao-Yu, Wang, Tao, Qu, Xin-Hui, Jiang, Li-Ping, Tou, Fang-Fang, Chen, Zhi-Ping, Han, Xiao-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641368/
https://www.ncbi.nlm.nih.gov/pubmed/36387221
http://dx.doi.org/10.3389/fonc.2022.956190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641368/
https://www.ncbi.nlm.nih.gov/pubmed/36387221
http://dx.doi.org/10.3389/fonc.2022.956190

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