In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues

Glycogen dysregulation is a hallmark of aging, and aberrant glycogen drives metabolic reprogramming and pathogenesis in multiple diseases. However, glycogen heterogeneity in healthy and diseased tissues remains largely unknown. Herein, we describe a method to define spatial glycogen architecture in...

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Detalles Bibliográficos
Autores principales: Young, Lyndsay E A, Conroy, Lindsey R, Clarke, Harrison A, Hawkinson, Tara R, Bolton, Kayli E, Sanders, William C, Chang, Josephine E, Webb, Madison B, Alilain, Warren J, Vander Kooi, Craig W, Drake, Richard R, Andres, Douglas A, Badgett, Tom C, Wagner, Lars M, Allison, Derek B, Sun, Ramon C, Gentry, Matthew S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641418/
https://www.ncbi.nlm.nih.gov/pubmed/36059248
http://dx.doi.org/10.15252/emmm.202216029

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