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Antagonizing microRNA‐19a/b augments PTH anabolic action and restores bone mass in osteoporosis in mice
Postmenopausal bone loss often leads to osteoporosis and fragility fractures. Bone mass can be increased by the first 34 amino acids of human parathyroid hormone (PTH), parathyroid hormone‐related protein (PTHrP), or by a monoclonal antibody against sclerostin (Scl‐Ab). Here, we show that PTH and Sc...
Autores principales: | Taipaleenmäki, Hanna, Saito, Hiroaki, Schröder, Saskia, Maeda, Miki, Mettler, Ramona, Ring, Matthias, Rollmann, Ewa, Gasser, Andreas, Haasper, Carl, Gehrke, Thorsten, Weiss, Alexander, Grimm, Steffen K, Hesse, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641424/ https://www.ncbi.nlm.nih.gov/pubmed/36193848 http://dx.doi.org/10.15252/emmm.202013617 |
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