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Antagonizing microRNA‐19a/b augments PTH anabolic action and restores bone mass in osteoporosis in mice

Postmenopausal bone loss often leads to osteoporosis and fragility fractures. Bone mass can be increased by the first 34 amino acids of human parathyroid hormone (PTH), parathyroid hormone‐related protein (PTHrP), or by a monoclonal antibody against sclerostin (Scl‐Ab). Here, we show that PTH and Sc...

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Detalles Bibliográficos
Autores principales: Taipaleenmäki, Hanna, Saito, Hiroaki, Schröder, Saskia, Maeda, Miki, Mettler, Ramona, Ring, Matthias, Rollmann, Ewa, Gasser, Andreas, Haasper, Carl, Gehrke, Thorsten, Weiss, Alexander, Grimm, Steffen K, Hesse, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641424/
https://www.ncbi.nlm.nih.gov/pubmed/36193848
http://dx.doi.org/10.15252/emmm.202013617

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