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A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection
A new mesoporous Cu-doped FeSn–G–SiO(2) (CFSGS) based biosensor was developed for the detection of microalbumin in urine samples. The mechanically flexible FeSn modified sensor was fabricated at room temperature. These demonstrations highlight the unexplored potential of FeSn for developing novel bi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641622/ https://www.ncbi.nlm.nih.gov/pubmed/36380930 http://dx.doi.org/10.1039/d2ra04932e |
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author | Areerob, Yonrapach Chanthai, Saksit Oh, Won-Chun |
author_facet | Areerob, Yonrapach Chanthai, Saksit Oh, Won-Chun |
author_sort | Areerob, Yonrapach |
collection | PubMed |
description | A new mesoporous Cu-doped FeSn–G–SiO(2) (CFSGS) based biosensor was developed for the detection of microalbumin in urine samples. The mechanically flexible FeSn modified sensor was fabricated at room temperature. These demonstrations highlight the unexplored potential of FeSn for developing novel biosensing devices. It is extremely sensitive and selective. Surfactant-aided self-assembly was used to synthesise the mesoporous CFSGS. The large surface area due to the mesopore presence in the CFSG surface that has been composited inside the mesoporous SiO(2) boosted the electrochemical detection. The linear range and detection limit of microalbumin under optimum circumstances were 0.42 and 1 to 10 μL, respectively. This easily fabricated mesoporous CFSGS provided a fast response with high sensitivity, and good selectivity. The sensor's reusability and repeatability were also quite high, with just a 90 percent drop after 4 weeks of storage at ambient temperature. The biosensor also demonstrated high selectivity against typical potential interfering chemicals found in urine (ascorbic acid, urea, and sodium chloride). The good performance of the mesoporous CFSGS biosensor was validated by measuring microalbumin, and the findings indicated that this sensing device performed very well. |
format | Online Article Text |
id | pubmed-9641622 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-96416222022-11-14 A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection Areerob, Yonrapach Chanthai, Saksit Oh, Won-Chun RSC Adv Chemistry A new mesoporous Cu-doped FeSn–G–SiO(2) (CFSGS) based biosensor was developed for the detection of microalbumin in urine samples. The mechanically flexible FeSn modified sensor was fabricated at room temperature. These demonstrations highlight the unexplored potential of FeSn for developing novel biosensing devices. It is extremely sensitive and selective. Surfactant-aided self-assembly was used to synthesise the mesoporous CFSGS. The large surface area due to the mesopore presence in the CFSG surface that has been composited inside the mesoporous SiO(2) boosted the electrochemical detection. The linear range and detection limit of microalbumin under optimum circumstances were 0.42 and 1 to 10 μL, respectively. This easily fabricated mesoporous CFSGS provided a fast response with high sensitivity, and good selectivity. The sensor's reusability and repeatability were also quite high, with just a 90 percent drop after 4 weeks of storage at ambient temperature. The biosensor also demonstrated high selectivity against typical potential interfering chemicals found in urine (ascorbic acid, urea, and sodium chloride). The good performance of the mesoporous CFSGS biosensor was validated by measuring microalbumin, and the findings indicated that this sensing device performed very well. The Royal Society of Chemistry 2022-11-08 /pmc/articles/PMC9641622/ /pubmed/36380930 http://dx.doi.org/10.1039/d2ra04932e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Areerob, Yonrapach Chanthai, Saksit Oh, Won-Chun A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection |
title | A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection |
title_full | A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection |
title_fullStr | A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection |
title_full_unstemmed | A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection |
title_short | A flexible mesoporous Cu doped FeSn–G–SiO(2) composite based biosensor for microalbumin detection |
title_sort | flexible mesoporous cu doped fesn–g–sio(2) composite based biosensor for microalbumin detection |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641622/ https://www.ncbi.nlm.nih.gov/pubmed/36380930 http://dx.doi.org/10.1039/d2ra04932e |
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