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C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration
Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a retinal neurodegenerative disorder. Human genetic data support the complement system as a key component of pathogenesis in AMD, which has been further supported by pre-clinical and recent clinical studies. However, the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641935/ https://www.ncbi.nlm.nih.gov/pubmed/36348407 http://dx.doi.org/10.1186/s40942-022-00431-y |