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C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a retinal neurodegenerative disorder. Human genetic data support the complement system as a key component of pathogenesis in AMD, which has been further supported by pre-clinical and recent clinical studies. However, the...

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Detalles Bibliográficos
Autores principales: Yednock, Ted, Fong, Donald S., Lad, Eleonora M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641935/
https://www.ncbi.nlm.nih.gov/pubmed/36348407
http://dx.doi.org/10.1186/s40942-022-00431-y

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