Multiple gene variants linked to Alzheimer’s-type clinical dementia via GWAS are also associated with non-Alzheimer’s neuropathologic entities

The classic pathologic hallmarks of Alzheimer’s disease (AD) are amyloid plaques and neurofibrillary tangles (AD neuropathologic changes, or ADNC). However, brains from individuals clinically diagnosed with “AD-type” (amnestic) dementia usually harbor heterogeneous neuropathologies in addition to, o...

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Detalles Bibliográficos
Autores principales: Katsumata, Yuriko, Shade, Lincoln M., Hohman, Timothy J., Schneider, Julie A., Bennett, David A., Farfel, Jose M., Kukull, Walter A., Fardo, David W., Nelson, Peter T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641973/
https://www.ncbi.nlm.nih.gov/pubmed/36191742
http://dx.doi.org/10.1016/j.nbd.2022.105880

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