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GM-CSF(+) Tc17 cells are required to bolster vaccine immunity against lethal fungal pneumonia without causing overt pathology
GM-CSF co-expressing T17 cells instigate pathologic inflammation during autoimmune disorders, but their function in immunity to infections is unclear. Here, we demonstrate the role of GM-CSF(+)Tc17 cells for vaccine immunity against lethal fungal pneumonia and the cytokine requirements for their ind...
Autores principales: | Mudalagiriyappa, Srinivasu, Sharma, Jaishree, Vieson, Miranda D., Nanjappa, Som Gowda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9641983/ https://www.ncbi.nlm.nih.gov/pubmed/36288707 http://dx.doi.org/10.1016/j.celrep.2022.111543 |
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