Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants

• Deletion of residues 156–157 warps the neighboring beta-sheet and leads NTD and RBD to shift. • T859N stabilizes the packing of the 630 loop motif to make RBD standing transition more difficult. • The overall structures of the closed state S complex from different variants resemble each other. • M...

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Detalles Bibliográficos
Autores principales: Xing, Xiaorui, Wang, Lei, Cui, Zhen, Fu, Wangjun, Zheng, Tao, Qin, Lili, Ge, Pingju, Qian, Aidong, Wang, Nan, Yuan, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642027/
https://www.ncbi.nlm.nih.gov/pubmed/36368512
http://dx.doi.org/10.1016/j.virs.2022.11.003

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