Trichosporon asahii Infection in an Extremely Preterm Infant in China

Trichosporon asahii is an uncommon cause of fungal sepsis among neonates, but it is an important life-threatening opportunistic systemic pathogen. We report a case of T. asahii sepsis in a 980-g female baby born at 27 weeks of gestation. The extremely preterm initially presented with recurrent feedi...

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Autores principales: Wang, Na, Tang, Jing-yi, Wang, Zi, Wang, Liu-yao, Song, Tian-tian, Li, Bei-bei, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642103/
https://www.ncbi.nlm.nih.gov/pubmed/36386411
http://dx.doi.org/10.2147/IDR.S385086
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author Wang, Na
Tang, Jing-yi
Wang, Zi
Wang, Liu-yao
Song, Tian-tian
Li, Bei-bei
Wang, Lin
author_facet Wang, Na
Tang, Jing-yi
Wang, Zi
Wang, Liu-yao
Song, Tian-tian
Li, Bei-bei
Wang, Lin
author_sort Wang, Na
collection PubMed
description Trichosporon asahii is an uncommon cause of fungal sepsis among neonates, but it is an important life-threatening opportunistic systemic pathogen. We report a case of T. asahii sepsis in a 980-g female baby born at 27 weeks of gestation. The extremely preterm initially presented with recurrent feeding intolerance and bloating; she subsequently developed oxygen saturation fluctuations, apnea, and a decreased heart rate. Blood culture was positive, and the causative agent was identified as T. asahii by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). According to reported minimum inhibitory concentration (MIC) values, the infant received a high dose of fluconazole (FLC, 12 mg/kg, qod) and was successfully treated.
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spelling pubmed-96421032022-11-15 Trichosporon asahii Infection in an Extremely Preterm Infant in China Wang, Na Tang, Jing-yi Wang, Zi Wang, Liu-yao Song, Tian-tian Li, Bei-bei Wang, Lin Infect Drug Resist Case Report Trichosporon asahii is an uncommon cause of fungal sepsis among neonates, but it is an important life-threatening opportunistic systemic pathogen. We report a case of T. asahii sepsis in a 980-g female baby born at 27 weeks of gestation. The extremely preterm initially presented with recurrent feeding intolerance and bloating; she subsequently developed oxygen saturation fluctuations, apnea, and a decreased heart rate. Blood culture was positive, and the causative agent was identified as T. asahii by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). According to reported minimum inhibitory concentration (MIC) values, the infant received a high dose of fluconazole (FLC, 12 mg/kg, qod) and was successfully treated. Dove 2022-11-04 /pmc/articles/PMC9642103/ /pubmed/36386411 http://dx.doi.org/10.2147/IDR.S385086 Text en © 2022 Wang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Wang, Na
Tang, Jing-yi
Wang, Zi
Wang, Liu-yao
Song, Tian-tian
Li, Bei-bei
Wang, Lin
Trichosporon asahii Infection in an Extremely Preterm Infant in China
title Trichosporon asahii Infection in an Extremely Preterm Infant in China
title_full Trichosporon asahii Infection in an Extremely Preterm Infant in China
title_fullStr Trichosporon asahii Infection in an Extremely Preterm Infant in China
title_full_unstemmed Trichosporon asahii Infection in an Extremely Preterm Infant in China
title_short Trichosporon asahii Infection in an Extremely Preterm Infant in China
title_sort trichosporon asahii infection in an extremely preterm infant in china
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642103/
https://www.ncbi.nlm.nih.gov/pubmed/36386411
http://dx.doi.org/10.2147/IDR.S385086
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