The regulation of antiviral activity of interferon epsilon

Interferon epsilon (IFN-ε) is a type I IFN. Some biological properties has been identified in many species, such as antiproliferative, anti-tumor, and antiviral effects, of IFN-ε, which are much weaker than those of IFN-α, have also been revealed. It has been shown to play a role in mucosal immunity...

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Detalles Bibliográficos
Autores principales: Zhao, Fu-Rong, Wang, Wei, Zheng, Qin, Zhang, Yan-Ge, Chen, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642105/
https://www.ncbi.nlm.nih.gov/pubmed/36386666
http://dx.doi.org/10.3389/fmicb.2022.1006481
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author Zhao, Fu-Rong
Wang, Wei
Zheng, Qin
Zhang, Yan-Ge
Chen, Jianming
author_facet Zhao, Fu-Rong
Wang, Wei
Zheng, Qin
Zhang, Yan-Ge
Chen, Jianming
author_sort Zhao, Fu-Rong
collection PubMed
description Interferon epsilon (IFN-ε) is a type I IFN. Some biological properties has been identified in many species, such as antiproliferative, anti-tumor, and antiviral effects, of IFN-ε, which are much weaker than those of IFN-α, have also been revealed. It has been shown to play a role in mucosal immunity and bacterial infection and in the prevention of certain sexually transmitted diseases, such as human immunodeficiency virus (HIV). This paper reviews the known activity of IFN-ε, particularly in some viruses. In general, this review provides a better understanding of effective IFN-ε treatment in the future.
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spelling pubmed-96421052022-11-15 The regulation of antiviral activity of interferon epsilon Zhao, Fu-Rong Wang, Wei Zheng, Qin Zhang, Yan-Ge Chen, Jianming Front Microbiol Microbiology Interferon epsilon (IFN-ε) is a type I IFN. Some biological properties has been identified in many species, such as antiproliferative, anti-tumor, and antiviral effects, of IFN-ε, which are much weaker than those of IFN-α, have also been revealed. It has been shown to play a role in mucosal immunity and bacterial infection and in the prevention of certain sexually transmitted diseases, such as human immunodeficiency virus (HIV). This paper reviews the known activity of IFN-ε, particularly in some viruses. In general, this review provides a better understanding of effective IFN-ε treatment in the future. Frontiers Media S.A. 2022-10-25 /pmc/articles/PMC9642105/ /pubmed/36386666 http://dx.doi.org/10.3389/fmicb.2022.1006481 Text en Copyright © 2022 Zhao, Wang, Zheng, Zhang and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Zhao, Fu-Rong
Wang, Wei
Zheng, Qin
Zhang, Yan-Ge
Chen, Jianming
The regulation of antiviral activity of interferon epsilon
title The regulation of antiviral activity of interferon epsilon
title_full The regulation of antiviral activity of interferon epsilon
title_fullStr The regulation of antiviral activity of interferon epsilon
title_full_unstemmed The regulation of antiviral activity of interferon epsilon
title_short The regulation of antiviral activity of interferon epsilon
title_sort regulation of antiviral activity of interferon epsilon
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642105/
https://www.ncbi.nlm.nih.gov/pubmed/36386666
http://dx.doi.org/10.3389/fmicb.2022.1006481
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