Host DNA depletion can increase the sensitivity of Mycobacterium spp. detection through shotgun metagenomics in sputum

Identification and phenotypic drug-susceptibility testing for mycobacteria are time-consuming and challenging but essential for managing mycobacterial infections. Next-generation sequencing (NGS) technologies can increase diagnostic speed and quality, but standardization is still lacking for many as...

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Detalles Bibliográficos
Autores principales: Kok, Nienke A., Peker, Nilay, Schuele, Leonard, de Beer, Jessica L., Rossen, John W. A., Sinha, Bhanu, Couto, Natacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642804/
https://www.ncbi.nlm.nih.gov/pubmed/36386679
http://dx.doi.org/10.3389/fmicb.2022.949328

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