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First study of extended half-life rFVIIIFc in previously untreated patients with hemophilia A: PUPs A-LONG final results
PUPs A-LONG evaluated the safety and efficacy of recombinant factor VIII Fc fusion protein (rFVIIIFc) in previously untreated patients (PUPs) with hemophilia A. This open-label, phase 3 study enrolled male PUPs (<6 years) with severe hemophilia A to receive rFVIIIFc. The primary endpoint was the...
Autores principales: | Königs, Christoph, Ozelo, Margareth C., Dunn, Amy, Kulkarni, Roshni, Nolan, Beatrice, Brown, Simon A., Schiavulli, Michele, Gunawardena, Sriya, Mukhopadhyay, Sutirtha, Jayawardene, Deepthi, Winding, Bent, Carcao, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642851/ https://www.ncbi.nlm.nih.gov/pubmed/35421219 http://dx.doi.org/10.1182/blood.2021013563 |
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